Protein Purification (CHBE-0161)

Spring 2024 · CHBE 0161 · Tufts University · 3 credits · Undergraduate

Methods of purifying proteins at a large scale for therapeutic or industrial uses. Focus on unit operations found in a typical process flowsheet including centrifugation, membrane filtration, most modes of chromatography, and lyophilization. Topics include introduction to protein chemistry and analytical methods, effects of production host choice, and protein stability. Process economics, GMP operations and validation, and case studies of biotechnology industry separations.

Course codes: CHBE-0161, CHBE 0161, CHBE0161, CHBE-161, CHBE 161, CHBE161

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