Immunotherapy of Cancer and Autoimmune Disease (MBS-0231)

Spring 2024 · MBS 0231 · Tufts University · 1.5 credits · Undergraduate

In the last few years we have seen a revolution in the treatment of cancer and autoimmune diseases – we cannot turn on the television or open a magazine or newspaper without seeing an ad for some new medication to treat a specific cancer or autoimmune disease. The reasons for this revolution in clinical treatment are clear – advances in “immunotherapy”: the manipulation of some component or arm of the immune response to treat disease. What are these advances? The theory that underlies the successful use of immunotherapy is an extension of the basic immunological concepts taught to students in their first year immunology course. Because the immunology course is so short, however, there is little time to do more than touch on this exciting new and clinically relevant area. Thus, the goal of this proposed elective is to offer MBS students the chance to learn more about the principles - and the practical aspects - of this new area of clinical treatment. The use of any revolutionary treatment always shines a spotlight on unforeseen side effects, and this issue will also be discussed at length. The course will provide an in-depth perspective on the types of immunotherapy currently being evaluated as well as a review of the evolution of immunotherapeutic approaches, including the treatment of allergy. Because the current immunology course does not contain a lecture on vaccination per se, this elective will provide an opportunity for students to understand theoretical and practical aspects of this key topic of major clinical importance. Student discussion of the latest clinical papers will be a key feature of the course.

Course codes: MBS-0231, MBS 0231, MBS0231, MBS-231, MBS 231, MBS231

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